Rayana AI
Account
SEPN
HOLD / NEUTRALMeanRev
Composite
43.50
Technical
95.40
Fundamental
26.20
Rank
Price
47.76
Hurst
0.28
As of
Aug 12, 2026
Daily
Septerna, Inc.
HealthcareBiotechnology

Septerna is a clinical-stage biotech firm that develops oral small molecule treatments targeting G protein-coupled receptors for conditions in endocrinology, immunology, inflammation, and metabolic disease. The company's pipeline includes candidates for hypoparathyroidism, chronic spontaneous urticaria, and graves' disease, with additional programs in neurology, women's health, cardiovascular, and respiratory areas. Septerna has a global partnership with Novo Nordisk to research and develop oral therapies for metabolic diseases.

Market cap
$1.8B
P/E (trailing)
P/E (forward)
-20.35
PEG ratio
Dividend yield
Beta
52w range
15.41 – 51.10
Return on equity
-6.34%
Profit margin
-24.51%
Revenue growth
+22375.60%
Earnings growth
Price history

1Y: 39.50 (+147.8%) · range 15.70–48.19

Cycle position
51/ 100 cycle scoreMID-BULL
ENTRYAPPROACHMID-BULLNEAR-TOPEXIT

entry readiness 22 · NOT READY · exit proximity 15

Conviction
19/ 100 · maturity 100%
VScore.408
Buildup.2035
EMA entry setup.2522
Fundamentals.1526
Volume profile
POC
24.76
Price vs POC
+59.5%
Overhead supply
18%
Runway
open sky

Value area 22.7837.51 · 18% of 120d volume overhead · clean runway

Contributing sources
SourceScoreLast seen
earnings-surprise
0.033
Sep 8, 2026
Forward returns
HorizonReturnMFEState
20d-21.66%-6.33%mature
40d-20.09%-6.33%21/40d